This past November I posted this: Back to the cooties in our guts....again!!!
In June, 2017, there was this: ASCO 2017: Melanoma, anti-PD1 and the microbes in your gut
In February of that year: Antibiotic use MAY decrease effectiveness of immunotherapy?????
From 2016, there was this: Intestinal bacteria as a way to determine risk for ipi induced colitis!
And in 2015...with a review of where all this bacterial mess started...there was this: Cooties in our gut keep us skinny, smart and cure cancer!?????
With all that...now, there's this.....
The commensal microbiome is associated with anti-PD-1 efficacy in metastatic melanoma patients. Matsson, Fessler, Bao, et al. Science. 2018 Jan 5.
And, I present excerpts from:
CANCER THERAPY, Precision medicine using microbiota. Intestinal microbiota influence cancer patient responses to immunotherapy. Jobin. Science. 2018 Jan 7.
Okay! What does all that mean?? Not, sure. I think a lot of this data meanders back and forth between melanoma peeps and melanoma mice (not to mention koalas in one of the prior reports!!!), so it is hard to know how much we can take as the gospel. In the end, (HA! HA! I CRACK myself up! Poops! I did it again!!!) I think we've always known that live cultures in foods like kimchi, yogurt, and kefir are good for us. We also know that, though antibiotics save lives and misery when they are needed, they can also cause harm by killing off microbes that we would actually be better off keeping around. So....eat the best you can. Include fiber and culture rich foods in your diet. Take antibiotics only when you need them. Keep a sense of humor. Wipe front to back. And know that despite all the Latin names...poop...really is...poop! - c