Not news, really. Here are a zillion related posts!!!
2014: Vitamin D and Melanoma
2016: Vit D and melanoma - Part 2
Jan 2017: Vitamin D - low levels associated with a worse prognosis in melanoma...again...
June 2017: Vitamin D and melanoma - folks with higher levesl do better - again!!!
September 2017: Vitamin D and melanoma
Now this:
Circulating 25-hydroxyvitamin D up to 3 decades prior to diagnosis in relation to overall and organ-specific cancer survival. Weinstein, Mondul, Yu, et al. Eur J Epidemiol. 2018 Aug 2.
While
vitamin D has been associated with improved overall cancer survival
in some investigations, few have prospectively evaluated
organ-specific survival. We examined the accepted biomarker of
vitamin D status, serum 25-hydroxyvitamin D [25(OH)D], and cancer
survival in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention
Study. Of 4616 cancer cases with measured serum 25(OH)D, 2884 died of
their cancer during 28 years of follow-up and 1732 survived or
died of other causes. Proportional hazards regression estimated
hazard ratios (HR) and 95% confidence intervals (CI) for the
association between pre-diagnostic 25(OH)D and overall and
site-specific survival. Serum 25(OH)D was significantly lower among
cases who subsequently died from their malignancy compared with those
who did not (medians 34.7 vs. 36.5 nmol/L, respectively). Higher
25(OH)D was associated with lower overall cancer mortality. Higher
25(OH)D was related to lower mortality from the following
site-specific malignancies: prostate, kidney, and melanoma, but
increased mortality from lung cancer. Improved survival was also
suggested for head and neck, gastric, pancreatic, and liver cancers,
though not statistically significantly, and case numbers for the
latter two organ sites were small. Higher 25(OH)D status years prior
to diagnosis was related to improved survival for overall and some
site-specific cancers, associations that should be examined in other
prospective populations that include women and other racial-ethnic
groups.
For what it's worth. - c
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