Friday, September 11, 2015
Latest update on my Nivo/Opdivo study peeps and me...
I noted this 1 year ago: "33 patients were enrolled. 10/33 patients relapsed. Of the 10 relapsed patients, five died due to metastatic melanoma; three were rendered free of disease surgically and remain disease-free at 2, 27 and 54 weeks after relapse. One patient had spontaneous regression... and has been free of disease for over 3 years. One additional relapsed patient is alive and on active therapy with dabrafenib plus trametinib."
We have learned from Dr. Weber this week that "now there are 6 deaths, but no additional relapses". To those of you who lost your loved ones, I am so sorry and hope that smiles from sweet memories have replaced at least a little of your pain.
This fact, from 6 months ago, remains true: "It remains important to remember that only 2 of the 10 of us with prior brain mets relapsed...one early on with undetected disease at admission to the study that was quite progressed and another not that long ago with a lung met that was resected, rendering them NED."
While not good enough, these are pretty good results for Stage IV peeps like me. As a reminder, I (along with 9 others) was given 1mg/kg Nivo every 2 weeks for 6 months (along with 6 IM peptide injections), followed by Nivo alone every 3 months for 2 additional years. The next 10 peeps did 3mg/kg Nivo...with same vaccines and schedule. The next 10 did 10mg/kg Nivo...same tadah. There are 3 additional ratties whose category I am not sure about.
We also have confirmation that Dr. Weber is moving to NYU. He will be following me there in the future.
So, enjoy: New York, New York...Alicia Keys and Jay Z
Thanks, Stevie. Much love to you all...especially the ratties! - c